Inclusion bodies enriched for p62 and polyubiquitinated proteins in

p62 com  This work introduces a new strategy for AD treatment based on the use of a Lactobacillus lactis strain carrying one plasmid that contains a eukaryotic p62 is a stress‐inducible protein able to change among binding partners, cellular localizations and form liquid droplet structures in a context‐dependent

In this mechanism, p62 serves as a shuttling protein for ubiquitinated substrates to the proteasome Under stress, the binding increases through the involvement This p-p62 antibody SQSTM1 is suitable for use in DB, ELISA and is guaranteed to work as stated on the product data sheet

The SQSTM1 gene is a target of Nrf2, and the SQSTM1 protein interacts with Keap1, inhibiting the ability of Keap1–Cul3–Rbx1 ubiquitin ligase to p62 is a highly conserved, multi-domain, and multi-functional adaptor protein critically involved in several important cellular processes